Effects of alcohol on digestion, absorption and metabolism of sea cucumber saponins in healthy mice

Sea cucumber saponins have attracted more attention in recent years due to biological activities. It is popular practice soak sea Baijiu at home and being applied industrial manufacturing China. However, knowledge on the effect of alcohol absorption metabolism limited. The effects digestion, BALB/c mice were investigated after gavage tail intravenous injection. results showed that content serum liver was significantly higher under influence than control group oral administration. Alcohol promoted prototype as well inhibited process transformed into deglycositic metabolites small intestine. Moreover, remained circulation for a long time slowed down clearance This confirmed feasibility marinating improve efficacy provides important theoretical basis utilization development liquor.